Well, let me try that different:
Imagine that someone would sell you instead of a whole litre milk just 970 millitres.
As long as you use also the bottles of that company only (which are in fact just a tiny bit smaller than others) - will you ever notice?
As long as you do not use a bottle from a different company you will not, I guess.
But on both bottles it says clearly “One litre of…”
Yes, I wrote MAY with really fat tyres - that means the exotic ones like Hookworm and Hutchinson.
Oh btw - better forget the attempt of Schwalbe Ballon since it is obviously not any longer available 
Preference - yes; I still love the silent and effortless ride on high-pressure tyres like Schwalbe Kojak at 8 bar!
Logically - riding these will require perfect clean and flat bikepaths, on sand you’re in big danger and cobblestones means spitting teeth. In rain I’d prefer taking a cab with these.
But I like also the Hutchinson, right now at my EVO - a very comfortable, stable ride.
Just - that one is, due to aluminium beltwheel, heavier wheels and a moustache bar heavy like lead.
Best for allround at the moment seems the efneo Strida, it has Schwalbe Marathon 35 - 349 tyres on custom wheels. It should not be hidden that the third gear ratio of the efneo is in fact harder to pedal compared to the EVO KS3 drive. That means that trained riders could be faster (just not me 
)
However - shortened, the whole thing still remains like this:
16" LT wheels - very limited tyre choice, preferably for smaller/lighter persons
16" metal wheels - limited tyre choice, better wheel quality but not explictly for athletes or very heavy persons
18" 355 size wheels - very limited tyre choice, best wheel quality, 50% more spokes and wider hub flanges compared to 16" wheels
Custom 16" wheels - tyre choice also limited (wide rim doesn’t accept narrow tyres)
Custom 18" 349 wheels - choice still limited (this time by frame clearance - somewhere around 37 or 40 width will the tyres start to touch the frame tubes)
